부산대학교 도서관

Objective: The implementation of nutritional support is a basic need of patients in palliative oncological care. This pilot study optimized the use of sipping to improve the nutritional status of cancer patients in palliative care. Materials and Method: The pilot study included 63 patients, 61.3 years of age on average (range: 32–82 years of age). The patients were assigned to either group A (no nutritional support n = 39 patients) or group B (sipping as nutritional support n = 24 patients). The patients were evaluated through by noninvasive methods: body weight, waist and arm circumference, and triceps skinfold, bioimpedance analysis, and dynamometry. Quality of life was assessed through modified questionnaires. Results: In contrast with group A, group B did not have a significant weight loss, that is, A: 81.9 ± 15.8–80.5 ± 15.8 kg (P = .028) and B: 73.9 ± 14.9–73 ± 16 kg. Body mass index A: 29 ± 5–28.5 ± 5 kg/m2 (P = .007) and B: 25.3 ± 4.7–25 ± 4.9 kg/m2 (P = .614). Waist circumference A: 93.5 ± 15.1–92.5 ± 14.8 cm (P = .008) and B: 80.1 ± 13.2–80.6 ± 12.3 cm (P = .234). Triceps skinfold A: 12.3 ± 7.2–11 ± 6.7 mm (P = .001) and B: 8.2 ± 6.1–7.9 ± 5.7 mm (P = .207). Fat free mass A: 54.8 ± 11.5–52.8 ± 11.6 kg (P = .018) and B: 54.7 ± 10.9–52.8 ± 11.5 kg (P = .207). Significantly lower dynamometer values were recorded in both groups; A: 25.6 ± 10.4–23.1 ± 10.3 kg (P = .010) and B: 27.4 ± 9.9–24.3 ± 9.1 kg (P = .009). In contrast to group B, the patients in group A showed slight variations in their health status, thus decreasing their scores into the significance limit (P = .072). Conclusion: Our results suggest that providing nutritional support in the form of sipping (∼12 g proteins, 300 kcal) on a daily basis prevents the loss of active tissue mass in palliative oncology patients. Based on these results, we recommend the inclusion of this simple nutritional support to prevent malnutrition in cancer patients in palliative care. The clinical study was registered by the internal ethics committee under the heading of its approval - Institutional Ethics Committee of the Hradec Králové Faculty Hospital, number 201311S2OP. [ABSTRACT FROM AUTHOR]