학술논문
Disseminated mycobacterial infections after tumor necrosis factor inhibitor use, revealing inborn errors of immunity.
Document Type
Article
Author
Source
Subject
*TUMOR necrosis factors
*MYCOBACTERIAL diseases
*LATENT tuberculosis
*IMMUNITY
*MYCOBACTERIUM tuberculosis
*BCG vaccines
*BURULI ulcer
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Language
ISSN
1201-9712
Abstract
• Novel cases of disseminated nontuberculous mycobacterium after tumor necrosis factor inhibitor in inborn errors of immunity (IEI). • Abnormal presentation of IEI associated with susceptibility to mycobacterial disease. • Importance of thorough immune evaluation for IEI in disseminated nontuberculous mycobacterium. Tumor necrosis factor-a inhibitors can be associated with increased risk of infections, particularly reactivation of latent tuberculosis or nontuberculous mycobacterium (NTM). However, because disseminated NTM is rare, inborn errors of immunity should be considered. We present three patients with disseminated NTM after tumor necrosis factor-a inhibitor use who were found to have inborn errors of immunity. [ABSTRACT FROM AUTHOR]