학술논문

Detection of Human Papillomavirus Genotypes Among High-Risk Women: A Comparison of Hybrid Capture and Linear Array Tests.
Document Type
Article
Source
Sexually Transmitted Diseases. May2008, Vol. 35 Issue 5, p521-527. 7p. 5 Charts, 1 Graph.
Subject
*PAPILLOMAVIRUSES
*ONCOGENIC DNA viruses
*PAP test
*CANCER diagnosis
*COLPOSCOPY
*ENDOSCOPY
*GENETIC polymorphisms
*EXFOLIATIVE cytology
*DIAGNOSIS
Language
ISSN
0148-5717
Abstract
The article aims to assess the concordance and performance of two different assays in detection of human papillomavirus (HPV) genotypes among women with abnormal Pap smear. In doing so, the authors analyze a series of 575 women refered for colposcopy due to an abnormal Pap smear with the linear array (LA) HPV genotyping test detecting 37 HPV types and compare with hybrid capture II assay for detection of carcinogenic HPV. Discussion on the results of the study is provided. Moreover, the study concludes that performance of HCII and LA did not significantly differ in detecting cervical intra epithelialneoplasia.