학술논문
Margin control of lentigo maligna with SOX10‐frozen section immunostaining: A case series.
Document Type
Article
Author
Source
Subject
*LENTIGO
*IMMUNOSTAINING
*SOX transcription factors
*MOHS surgery
*MELANOMA
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Language
ISSN
0004-8380
Abstract
This article discusses the use of SOX10 immunostaining in frozen tissue for the detection of lentigo maligna (LM), a type of melanoma. The study found that SOX10 had a sensitivity of 94% and a specificity of 100% in detecting LM when compared to conventional analysis using paraffin-embedded sections. The use of SOX10 immunostaining in frozen tissue can potentially reduce the need for multi-day procedures and improve the efficiency of margin control techniques. However, the study has limitations, including a small sample size and lack of blind assessment of the slides. Overall, SOX10 immunostaining shows promise in improving the detection of LM and streamlining surgical procedures. [Extracted from the article]