학술논문

Roadmap to the study of gene and protein phylogeny and evolution—A practical guide.
Document Type
Article
Source
PLoS ONE. 2/24/2023, Vol. 17 Issue 2, p1-35. 35p.
Subject
*BIOLOGICAL databases
*DNA data banks
*PHYLOGENY
*MOLECULAR evolution
*DATA mining
Language
ISSN
1932-6203
Abstract
Developments in sequencing technologies and the sequencing of an ever-increasing number of genomes have revolutionised studies of biodiversity and organismal evolution. This accumulation of data has been paralleled by the creation of numerous public biological databases through which the scientific community can mine the sequences and annotations of genomes, transcriptomes, and proteomes of multiple species. However, to find the appropriate databases and bioinformatic tools for respective inquiries and aims can be challenging. Here, we present a compilation of DNA and protein databases, as well as bioinformatic tools for phylogenetic reconstruction and a wide range of studies on molecular evolution. We provide a protocol for information extraction from biological databases and simple phylogenetic reconstruction using probabilistic and distance methods, facilitating the study of biodiversity and evolution at the molecular level for the broad scientific community. [ABSTRACT FROM AUTHOR]