학술논문

SUMO-activated target traps (SATTs) enable the identification of a comprehensive E3-specific SUMO proteome.
Document Type
Article
Source
Science Advances. 8/4/2023, Vol. 9 Issue 31, p1-16. 16p.
Subject
*GREEN fluorescent protein
*DNA repair
Language
ISSN
2375-2548
Abstract
The article introduces SUMO-activated target traps (SATTs) as a method for comprehensive identification of E3-specific SUMO proteomes. Topics include the development of SATTs to identify substrates for eight SUMO E3 enzymes, quantitative proteomics for measuring substrate specificity, and the creation of the Polar SATTs tool for interactive dataset exploration.