학술논문
Viral co-infections among SARS-CoV-2-infected children and infected adult household contacts.
Document Type
Article
Author
Pigny, Fiona; Wagner, Noémie; Rohr, Marie; Mamin, Aline; Cherpillod, Pascal; Posfay-Barbe, Klara M.; Kaiser, Laurent; Eckerle, Isabella; L'Huillier, Arnaud G.; for the Geneva Pediatric COVID Group; Gervaix, Alain; Lacroix, Laurence; Haddad, Kevin; Wagner, Noemie; Pinosch, Selina; Grazioli, Serge; Pfister, Riccardo; Widlhaber, Barbara; Beghetti, Maurice; Maggio, Albane
Source
Subject
*MIXED infections
*HOUSEHOLDS
*SARS-CoV-2
*STAY-at-home orders
*SCHOOL closings
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Language
ISSN
0340-6199
Abstract
We evaluated the rates of viral respiratory co-infections among SARS-CoV-2-infected children. Twelve percent of SARS-CoV-2-infected children had viral co-infection with one or more common respiratory viruses. This was significantly more frequent than among their SARS-CoV-2-infected adult household contacts (0%; p=0.028). Compared to the same period the previous year, common respiratory viruses were less frequently detected (12% vs 73%, p<0.001). Conclusion: Despite partial lockdown with school and daycare closure, and consequently similar exposure to common viruses between children and adults, SARS-CoV-2-infected children had more frequent viral respiratory co-infections than their SARS-CoV-2-infected adult household contacts. Circulation of common respiratory viruses was less frequent during the SARS-CoV-2 outbreak when compared to the same period last year, showing the impact of partial lockdown on the circulation of common viruses. What is Known: • Viral respiratory co-infections are frequent in children. • SARS-CoV-2 can be identified alongside other respiratory viruses, but data comparing children and adults are lacking. What is New: • Children infected with SARS-CoV-2 are more likely to have viral respiratory co-infections than their SARS-CoV-2-infected adult household contacts, which is surprising in the context of partial lockdown with schools and daycare closed. • When compared to data collected during the same period last year, our study also showed that partial lockdown reduced circulation of common respiratory viruses. [ABSTRACT FROM AUTHOR]