학술논문

SWINGING ARMS AND SWINGING DOMAINS IN MULTIFUNCTIONAL ENZYMES: Catalytic Machines for Multistep Reactions.
Document Type
Article
Source
Annual Review of Biochemistry. 2000, Vol. 69 Issue 1, p961. 44p.
Subject
*BIOTRANSFORMATION (Metabolism)
*BIOTIN
*LIPOIC acid
Language
ISSN
0066-4154
Abstract
Discusses the importance of multistep chemical reactions in a growing number of complex biotransformations. Structure and biosynthesis of lipoc acid, biotin, and pantetheine acid; Occurrence and biological roles of lipoic acid-dependent enzymes; Overview of substrate channeling and active-site coupling.