학술논문
Portal Dissemination of Fusarium graminearum in a Patient with Acute Lymphoblastic Leukemia and Febrile Neutropenia.
Document Type
Case Study
Author
Source
Subject
*FEBRILE neutropenia
*LYMPHOBLASTIC leukemia
*ACUTE leukemia
*FUSARIOSIS
*SYMPTOMS
*LIVER abscesses
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Language
ISSN
2036-7449
Abstract
We present the case of a man with acute lymphoblastic leukemia and prolonged profound neutropenia, who developed an invasive infection by Fusarium graminearum, acquired via noncutaneous entry, with gastrointestinal symptoms, sigmoid perforation and liver abscesses due to portal dissemination. The etiologic agent was identified using the 18S-ITS1-5.8S-ITS2-28S rRNA sequence gene, from a liver biopsy. The infection was resolved with surgical drainage and antifungal treatment based on voriconazole. As far as we know, there are no previous reports in the literature of cases of human infection due to Fusarium graminearum. [ABSTRACT FROM AUTHOR]