학술논문
Movement disorders following mechanical thrombectomy resulting in ischemic lesions of the basal ganglia: An emerging clinical entity.
Document Type
Article
Author
Rigon, Leonardo; Genovese, Danilo; Piano, Carla; Brunetti, Valerio; Guglielmi, Valeria; Cimmino, Angelo Tiziano; Scala, Irene; Citro, Salvatore; Bentivoglio, Anna Rita; Rollo, Eleonora; Di Iorio, Riccardo; Broccolini, Aldobrando; Morosetti, Roberta; Monforte, Mauro; Frisullo, Giovanni; Caliandro, Pietro; Pedicelli, Alessandro; Caricato, Anselmo; Masone, Giovanna; Calabresi, Paolo
Source
Subject
*MOVEMENT disorders
*BASAL ganglia
*ISCHEMIC stroke
*THROMBECTOMY
*STROKE
*CEREBRAL arteries
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Language
ISSN
1351-5101
Abstract
Background and purpose: Post‐stroke movement disorders (PMDs) following ischemic lesions of the basal ganglia (BG) are a known entity, but data regarding their incidence are lacking. Ischemic strokes secondary to proximal middle cerebral artery (MCA) occlusion treated with thrombectomy represent a model of selective damage to the BG. The aim of this study was to assess the prevalence and features of movement disorders after selective BG ischemia in patients with successfully reperfused acute ischemic stroke (AIS). Methods: We enrolled 64 consecutive subjects with AIS due to proximal MCA occlusion treated with thrombectomy. Patients were clinically evaluated by a movement disorders specialist for PMDs onset at baseline, and after 6 and 12 months. Results: None of the patients showed an identifiable movement disorder in the subacute phase of the stroke. At 6 and 12 months, respectively, 7/25 (28%) and 7/13 (53.8%) evaluated patients developed PMDs. The clinical spectrum of PMDs encompassed parkinsonism, dystonia and chorea, either isolated or combined. In most patients, symptoms were contralateral to the lesion, although a subset of patients presented with bilateral involvement and prominent axial signs. Conclusion: Post‐stroke movement disorders are not uncommon in long‐term follow‐up of successfully reperfused AIS. Follow‐up conducted by a multidisciplinary team is strongly advisable in patients with selective lesions of the BG after AIS, even if asymptomatic at discharge. [ABSTRACT FROM AUTHOR]