학술논문
A highly selective method for 11β-OH protection of steroidal 11β, 17α-diols
Document Type
Article
Source
Subject
*STEROIDS
*STEROLS
*CYCLOPENTAPHENANTHRENE
*LIPIDS
*
*
*
Language
ISSN
0039-128X
Abstract
Abstract: A highly selective method to protect the 11β-OH position of steroid (1) has been developed. This is achieved via double silyl protection of the 11β, 17α-diol, followed by selective desilylation of the 17α-OH under basic conditions without the need for a fluoride source. [Copyright &y& Elsevier]