학술논문

Post‐operative minimal residual disease models to study metastatic relapse in soft‐tissue sarcoma patient‐derived xenografts.
Document Type
Article
Source
Clinical & Translational Medicine. Jun2023, Vol. 13 Issue 6, p1-7. 7p.
Subject
*XENOGRAFTS
*SARCOMA
*METASTASIS
*SURGICAL margin
*LUNGS
Language
ISSN
2001-1326
Abstract
Kaplan-Meier graphs indicating the probability of primary tumour growth comparing (D) implantation site or (E) mouse strain, where "event" is detection of tumour growth and censored when no tumour was detected at time of necropsy. Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes. Post-operative minimal residual disease models to study metastatic relapse in soft-tissue sarcoma patient-derived xenografts (A) Animals were followed until metastasis, or until 12 months post primary tumour resection if no metastases developed, or until 18 months (78 weeks) post tumour implantation if no primary tumour developed. [Extracted from the article]