학술논문
Amplification of epidermal growth factor receptor gene in renal cell carcinoma
Document Type
Article
Author
Source
Subject
*RENAL cancer
*GENE amplification
*EPIDERMAL growth factor
*PROGNOSIS
*COHORT analysis
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Language
ISSN
0959-8049
Abstract
Expression of epidermal growth factor receptor (EGFR) may be of prognostic value in renal cell cancer (RCC). Gene amplification of EGFR was investigated in a cohort of 315 patients with advanced RCC from a previously reported randomised study. Using fluorescent in situ hybridisation, only 2 patients (0.6%) had gene amplification; therefore gene amplification is of no prognostic value in RCC. [Copyright &y& Elsevier]