학술논문
Clinical features and outcome of stroke with COVID-19. COVID-19 Stroke Study Group (CSSG), India.
Document Type
Article
Author
Bhatia, Rohit; Padma Srivastava, M; Sylaja, P; Komakula, Snigdha; Upadhyay, Ashish; Pardasani, Vibhor; Iype, Thomas; Parthasarathy, Rajsrinivas; Reddy, Rajshekhar; Kushwaha, Suman; Roy, Jayanta; Satish, P; Trikha, Anjan; Wig, Naveet; Dhar, Lalit; Vibha, Deepti; Vishnu, Venugopalan; Pandit, Awadh; Gupta, Anu; Elavarasi, A
Source
Subject
*COVID-19
*STROKE
*HEALTH outcome assessment
*SYMPTOMS
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Language
ISSN
0972-2327
Abstract
Background and Purpose: Occurrence of stroke has been reported among patients with COVID-19. The present study compares clinical features and outcomes of stroke patients with and without COVID-19. Methods: The COVID-19 Stroke Study Group (CSSG) is a multicentric study in 18 sites across India to observe and compare the clinical characteristics of patients with stroke admitted during the current pandemic period and a similar epoch in 2019. The present study reports patients of stroke with and without COVID-19 (CoVS and non-CoVS, respectively) seen between February 2020 and July 2020. Demographic, clinical, treatment, and outcome details of patients were collected. Results: The mean age and gender were comparable between the two groups. CoVS patients had higher stroke severity and extent of cerebral involvement on imaging. In-hospital complications and death were higher among CoVS patients (53.06% vs. 17.51%; P < 0.001) and (42.31% vs. 7.6%; P < 0.001), respectively. At 3 months, higher mortality was observed among CoVS patients (67.65% vs. 13.43%; P < 0.001) and good outcome (modified Rankin score [mRS]: 0–2) was seen more often in non-CoVS patients (68.86% vs. 33.33%; P < 0.001). The presence of COVID-19 and baseline stroke severity were independent predictors of mortality. Conclusions: CoVS is associated with higher severity, poor outcome, and increased mortality. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and baseline stroke severity are independent predictors of mortality. [ABSTRACT FROM AUTHOR]