학술논문
The falling incidence of hematologic cancer after heart transplantation.
Document Type
Article
Author
Crespo ‐ Leiro, M. G.; Delgado ‐ Jiménez, J.; López, L.; Alonso ‐ Pulpón, L.; González ‐ Vilchez, F.; Almenar ‐ Bonet, L.; Rábago, G.; Pérez ‐ Villa, F.; Paniagua Martín, M. J.; Arizón del Prado, J. M.; Sousa ‐ Casasnovas, I.; Manito ‐ Lorite, N.; Díaz ‐ Molina, B.; Pascual ‐ Figal, D.; Lage ‐ Galle, E.; Blasco ‐ Peiró, T.; De la Fuente ‐ Galán, L.; Muñiz, J.
Source
Subject
*HEART transplantation
*HEMATOLOGY
*DISEASE incidence
*HEMATOLOGIC malignancies
*LYMPHOMAS
*IMMUNOSUPPRESSIVE agents
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Language
ISSN
0902-0063
Abstract
Background A number of changes in the management of heart transplantation ( HT) patients have each tended to reduce the risk of post- HT hematologic cancer, but little information is available concerning the overall effect on incidence in the HT population. Methods Comparison of data from the Spanish Post-Heart-Transplantation Tumour Registry for the periods 1991-2000 and 2001-2010. Results The incidence among patients who underwent HT in the latter period was about half that observed in the former, with a particularly marked improvement in regard to incidence more than five yr post- HT. Conclusions Changes in HT patient management have jointly reduced the risk of hematologic cancer in the Spanish HT population. Long-term risk appears to have benefited more than short-term risk. [ABSTRACT FROM AUTHOR]