학술논문

Chemistry towards Biology—Instruct: Snapshot †.
Document Type
Article
Source
International Journal of Molecular Sciences. Dec2022, Vol. 23 Issue 23, p14815. 24p.
Subject
*BIOCHEMISTRY
*MOLECULAR structure
*CHEMICAL biology
*LIFE sciences
*MEDICAL sciences
Language
ISSN
1661-6596
Abstract
The knowledge of interactions between different molecules is undoubtedly the driving force of all contemporary biomedical and biological sciences. Chemical biology/biological chemistry has become an important multidisciplinary bridge connecting the perspectives of chemistry and biology to the study of small molecules/peptidomimetics and their interactions in biological systems. Advances in structural biology research, in particular linking atomic structure to molecular properties and cellular context, are essential for the sophisticated design of new medicines that exhibit a high degree of druggability and very importantly, druglikeness. The authors of this contribution are outstanding scientists in the field who provided a brief overview of their work, which is arranged from in silico investigation through the characterization of interactions of compounds with biomolecules to bioactive materials. [ABSTRACT FROM AUTHOR]