학술논문

The Polycomb-group gene Rae28 sustains Nkx2.5/Csx expression and is essential for cardiac morphogenesis.
Document Type
Article
Source
Journal of Clinical Investigation. 7/15/2002, Vol. 110 Issue 2, p177. 8p. 4 Color Photographs, 1 Black and White Photograph, 1 Chart.
Subject
*GENES
*HEART
*IN situ hybridization
*GENE expression
Language
ISSN
0021-9738
Abstract
Presents a study which performed detailed examination of the role of Polycomb-group gene Rae28 in the genetic programs governing heart development. Methods used; Morphology of the embryonic hearts; Result of the in situ hybridization analysis of gene expression; Complementation analysis of Rae28 embryos by exogenous human NKX2.5.