학술논문

Aldehyde dehydrogenase 2 as a potential protective factor for renal insufficiency in Japanese subjects with heart failure: a pilot study.
Document Type
Article
Source
Journal of Human Hypertension. Apr2014, Vol. 28 Issue 4, p279-281. 3p.
Subject
*ALDEHYDE dehydrogenase
*KIDNEY failure
*HEART failure
*GLOMERULAR filtration rate
*ENDOTHELIAL cells
Language
ISSN
0950-9240
Abstract
The article discusses a pilot study on the potential of aldehyde dehydrogenase 2 (ALDH2) as a protective factor for renal insufficiency in Japanese hypertensive patients with heart failure. It examines the association between ALDH2 genotypes and the estimated glomerular filtration rate. The study found the potential of ALDH2 to protect kidneys against systematic endothelial dysfunction. Limitations of the study are noted.