학술논문

Locally Acquired Melioidosis Linked to Environment -- Mississippi, 2020-2023.
Document Type
Article
Source
New England Journal of Medicine. 12/21/2023, Vol. 389 Issue 25, p2355-2362. 8p.
Subject
*MELIOIDOSIS
*ENDEMIC diseases
*BACTERIAL diseases
*BURKHOLDERIA pseudomallei
*SOIL pollution
*FRESH water
Language
ISSN
0028-4793
Abstract
Melioidosis, caused by Burkholderia pseudomallei, is a rare but potentially fatal bacterial disease endemic to tropical and subtropical regions worldwide. It is typically acquired through contact with contaminated soil or fresh water. Before this investigation, B. pseudomallei was not known to have been isolated from the environment in the continental United States. Here, we report on three patients living in the same Mississippi Gulf Coast county who presented with melioidosis within a 3-year period. They were infected by the same Western Hemisphere B. pseudomallei strain that was discovered in three environmental samples collected from the property of one of the patients. These findings indicate local acquisition of melioidosis from the environment in the Mississippi Gulf Coast region. [ABSTRACT FROM AUTHOR]