학술논문
Linezolid Dependence in Staphylococcus epidermidis Bloodstream Isolates.
Document Type
Article
Author
Source
Subject
*LINEZOLID
*STAPHYLOCOCCUS epidermidis
*INFECTION
*PULSED-field gel electrophoresis
*GEL electrophoresis
*STREPTOMYCIN
*
*
*
*
*
Language
ISSN
1080-6040
Abstract
We document linezolid dependence among 5 highly linezolid-resistant (LRSE) Staphylococcus epidermidis bloodstream isolates that grew substantially faster at 32 µg/ mL linezolid presence. These isolates carried the mutations T2504A and C2534T in multiple 23S rRNA copies and 2 mutations leading to relevant amino acid substitutions in L3 protein. Linezolid dependence could account for increasing LRSE emergence. [ABSTRACT FROM AUTHOR]