학술논문

Epidemiology of alcohol use and alcohol use disorders among people living with HIV on antiretroviral therapy in Northwest Tanzania: implications for ART adherence and case management.
Document Type
Article
Source
AIDS Care. May2024, Vol. 36 Issue 5, p652-660. 9p.
Subject
*HIV infection prognosis
*ALCOHOLISM risk factors
*COMPLICATIONS of alcoholism
*RISK assessment
*PATIENT compliance
*CROSS-sectional method
*RESEARCH funding
*PRIMARY health care
*MEDICAL case management
*HIV-positive persons
*QUESTIONNAIRES
*LOGISTIC regression analysis
*SEX distribution
*HIV infections
*DESCRIPTIVE statistics
*HIGHLY active antiretroviral therapy
*ODDS ratio
*ALCOHOL drinking
*ALCOHOLISM
*SOCIODEMOGRAPHIC factors
*DRUGS
*CONFIDENCE intervals
*WELL-being
Language
ISSN
0954-0121
Abstract
Alcohol use disorders (AUD) among people living with HIV (PLHIV) are associated with poor health outcomes. This cross-sectional study examined current alcohol use and AUD among 300 PLHIV on ART at four HIV care centres in Northwest Tanzania. Participants' data were collected using questionnaires. Alcohol use was assessed using Alcohol Use Disorders Identification Test (AUDIT). Logistic regression was used to examine associations between each outcome (current drinking and AUD) and sociodemographic and clinical factors. Association between alcohol use and ART adherence was also studied. The median age of participants was 43 years (IQR 19-71) and 41.3% were male. Twenty-two (7.3%) participants failed to take ART at least once in the last seven days. The prevalence of current drinking was 29.3% (95% CI 24.2-34.8%) and that of AUD was 11.3% (8.2%−15.5%). Males had higher odds of alcohol use (OR 3.03, 95% CI 1.79-5.14) and AUD (3.89, 1.76-8.60). Alcohol use was associated with ART non-adherence (OR = 2.78, 1.10–7.04). There was a trend towards an association between AUD and non-adherence (OR = 2.91, 0.92–9.21). Alcohol use and AUD were common among PLHIV and showed evidence of associations with ART non-adherence. Screening patients for alcohol use and AUD in HIV clinics may increase ART adherence. [ABSTRACT FROM AUTHOR]