학술논문
Chromatin remodeling factor CECR2 forms tissue-specific complexes with CCAR2 and LUZP1.
Document Type
Article
Source
Subject
*CHROMATIN
*HISTONES
*DNA-binding proteins
*PROTEOMICS
*CHIMERIC proteins
*DOUBLE-strand DNA breaks
*CARRIER proteins
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Language
ISSN
0829-8211
Abstract
The article discusses research which attempted to identify the candidate components of the CECR2-containing remodeling factor (CERF) complex in embryonic stem (ES) cells using mass spectroscopy. Topics covered include the findings which show the involvement of leucine zipper protein 1 (Luzp1) in neurulation and that its loss in mice results in exencephaly, and evidence to confirm that in ES cells, LUZP1 acts to stabilize the CERF complex.