학술논문
Resolvin D2 regulates type 2 inflammatory responses and promotes resolution of mouse allergic inflammation.
Document Type
Article
Author
Source
Subject
*INFLAMMATION
*MEDICAL sciences
*INNATE lymphoid cells
*REGULATORY T cells
*PULMONARY eosinophilia
*EPITHELIAL cells
*
*
*
*
*
Language
ISSN
0105-4538
Abstract
This article, published in the journal Allergy, discusses the role of a specialized pro-resolving mediator called Resolvin D2 (RvD2) in regulating type 2 inflammatory responses and promoting the resolution of allergic inflammation in mice. The study found that RvD2 decreased airway inflammation, eosinophil accumulation, and bronchial epithelial mucous cell metaplasia in mice with allergic inflammation. RvD2 also reduced airway hyperresponsiveness and levels of pro-inflammatory mediators. The findings suggest that RvD2 may have potential therapeutic benefits for treating asthma and other allergic diseases. [Extracted from the article]