학술논문

New Insights into Chemical and Biological Properties of Funicone-like Compounds.
Document Type
Article
Source
Toxins. Jul2022, Vol. 14 Issue 7, pN.PAG-N.PAG. 16p.
Subject
*CHEMICAL properties
*METABOLITES
*FUNGAL metabolites
*POLYKETIDES
*MOLECULAR structure
*MYCOTOXINS
Language
ISSN
2072-6651
Abstract
Funicone-like compounds are a homogeneous group of polyketides that, so far, have only been reported as fungal secondary metabolites. In particular, species in the genus Talaromyces seem to be the most typical producers of this group of secondary metabolites. The molecular structure of funicone, the archetype of these products, is characterized by a γ-pyrone ring linked through a ketone group to a α-resorcylic acid nucleus. This review provides an update on the current knowledge on the chemistry of funicone-like compounds, with special emphasis on their classification, occurrence, and diverse biological activities. In addition, their potential relevance as mycotoxins is discussed. [ABSTRACT FROM AUTHOR]