부산대학교 도서관

Purpose: In between migraine attacks, some people show visual field defects that are worse when measured closer to theend of a migraine event. In this cohort study, we consider whether electrophysiological responses correlate with visualfield performance at different times post-migraine, and explore evidence for cortical versus retinal origin.Methods: Twenty-six non-headache controls and 17 people with migraine performed three types of perimetry (static,flicker and blue-on-yellow) to assess different aspects of visual function at two visits conducted at different durationspost-migraine. On the same days, the pattern electroretinogram (PERG) and visual evoked response (PVER) wererecorded. Results: Migraine participants showed persistent, interictal, localised visual field loss, with greater deficits at the visitnearer to migraine offset. Spatial patterns of visual field defect consistent with retinal and cortical dysfunction wereidentified. The PERG was normal, whereas the PVER abnormality found did not change with time post-migraine and didnot correlate with abnormal visual field performance.Conclusions: Dysfunction on clinical tests of vision is common in between migraine attacks; however, the nature of thedefect varies between individuals and can change with time. People with migraine show markers of both retinal and/orcortical dysfunction. Abnormal visual field sensitivity does not predict abnormality on electrophysiological testing. [ABSTRACT FROM AUTHOR]