학술논문

Southern African HIV Clinicians Society guidelines for solid organ transplantation in human immunodeficiency virus: An evidence-based framework for human immunodeficiency virus-positive donors and recipients.
Document Type
Article
Source
Southern African Journal of HIV Medicine. 2020, Vol. 21 Issue 1, p1-8. 8p.
Subject
*KIDNEY transplantation
*KIDNEY exchange
*MEDICAL personnel
*HIV
*CHRONIC hepatitis B
*AIDS-related opportunistic infections
*TRANSPLANTATION of organs, tissues, etc.
*AIDS
*HIV infections
Language
ISSN
1608-9693
Abstract
These guidelines, intended for transplantation healthcare practitioners in Southern Africa, seek to sketch an evidence-based framework for human immunodeficiency virus (HIV)-positive donors and recipients regarding solid organ transplantation. Human immunodeficiency virus-negative recipients The risk of an HIV-negative recipient acquiring HIV from an organ from an HIV-positive donor is currently unknown, and is likely to be influenced by multiple donor and recipient characteristics, and the nature of the solid organ that is transplanted. Recommendations for donor and recipient eligibility Recipient eligibility Human immunodeficiency virus-positive recipient Eligibility criteria for HIV-positive transplant recipients: CD4 SP + sp count >= 200 cells/µL (>= 100 cells/µL can be considered for liver transplant recipients provided there is no history of opportunistic infections or malignancies). B Rationale: b Although the risk of transmission of the donor virus to the recipient is likely to be higher if the donor has an unsuppressed VL, limiting the deceased donor pool only to virally suppressed individuals would significantly restrict the number of organs available. [Extracted from the article]