학술논문

Role of hydrogel spacer to protect the rectum from thermal injury in focal therapy of prostate cancer: Preclinical study in cadaver model.
Document Type
Article
Source
International Journal of Urology. Jan2023, Vol. 30 Issue 1, p116-118. 3p.
Subject
*PROSTATE cancer
*COLD therapy
*HYDROGELS
*RECTUM
*RADIOTHERAPY
*MEDICAL cadavers
*CANCER treatment
Language
ISSN
0919-8172
Abstract
Abbreviations RW rectal wall TC thermocouple TRUS transrectal ultrasound Recent clinical pilot studies that explored focal therapy of prostate cancer have reported that thermal-ablation technology (including microwave coagulation, or cryoablation) is effective for controlling clinically significant cancer.[[1]] Thermal-ablation therapies that target prostate cancer, especially in peripheral zone near the rectum, need to avoid rectal injury by protecting the rectal wall (RW), and ensuring enough distance between the rectum and prostate. In conclusion, the result of this study suggested that the thermal-ablation therapy with hydrogel spacer injected into Denonvilliers' space is promising for focal therapy of prostate cancer. [Extracted from the article]