학술논문
Antimelanogenic effect of 4-hydroxylonchocarpin through the inhibition of tyrosinase-related proteins and MAPK phosphatase.
Document Type
Article
Author
Source
Subject
*PHARMACOLOGY
*TYRP1 gene
*MELANOMA
*MELANOGENESIS
*CELL lines
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Language
ISSN
0906-6705
Abstract
The article presents a study that mentions of several pharmacological of 4-hydroxylonchocarpin (HLCP) and investigates whether HLCP affects melanogenesis by inhibition of tyrosinase-related proteins in human melanoma cells. Topics discussed include use of different melanoma cell lines in the study including B16F10 mouse melanoma, SKMEL-2 and MNT-1 human melanoma cell lines, analysis of MAPK signalling pathways and discussion on the antimelanogenic effects of HLCP.