학술논문
Pharmacotherapy of the Lipid-Lowering Drugs: Update on Efficacy and Risk.
Document Type
Article
Author
Source
Subject
*ANTILIPEMIC agents
*DRUG efficacy
*DRUG therapy
*DYSTROPHY
*CONTRACTILITY (Biology)
*MOLECULAR biology
*HIGH cholesterol diet
*VITAMIN D receptors
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Language
ISSN
1661-6596
Abstract
Alternatively, other drugs can be prescribed, such as bile acid sequestrants, ezetimibe, colesevelam, lomitapide and also nutraceutical compounds to substitute statin therapy [[10], [12]]. Overall, these results demonstrated a peripheral neuropathy accompanied by impaired energy homeostasis and suggest a guide for drug intervention or lifestyle changes to prevent statin-induced muscle symptoms and to maintain statin therapy for long time period. Although new drugs are emerging (monoclonal antibodies, antisense oligonucleotides, etc.), statins remain the first-line option for the treatment of hypercholesterolemia, making it essential to identify the causes of their toxicity. Lipid-lowering drugs are widely used for the prevention and cure of cardiovascular diseases (CVD). [Extracted from the article]