학술논문
Effects of Glycine Receptors of the Medial Preoptic Nucleus on Sexual Behavior of Male Wistar Rats.
Document Type
Article
Source
Subject
*LABORATORY rats
*PREOPTIC area
*GLYCINE receptors
*GLYCINE agents
*HUMAN sexuality
*STRYCHNINE
*MICROINJECTIONS
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Language
ISSN
0007-4888
Abstract
We studied the effect of bilateral microinjections of selective pharmacological agents modulating glycine receptor activity into the medial preoptic nucleus on sexual behavior of male Wistar rats. Application of the glycine receptor blocker strychnine (20 μM, 2 μl) led to a significant inhibition of both appetitive and consummatory components of sexual behavior, whereas stimulation with glycine (1 mM and 50 μM, 2 μl) had no significant effect. [ABSTRACT FROM AUTHOR]