학술논문

Dapsone for thrombocytopenic purpura related to human immunodeficiency virus infection.
Document Type
Journal Article
Source
American Journal of Medicine. Jun91, Vol. 90 Issue 6, p675-677. 3p.
Subject
*DAPSONE
*HIV infection complications
*AUTOIMMUNE diseases
*THROMBOPENIC purpura
*LEUKOCYTE count
*PLATELET count
*THERAPEUTICS
Language
ISSN
0002-9343
Abstract
Purpose: The purpose of this study was to determine the effect of dapsone on platelet count in patients with human immunodeficiency virus (HIV)-related autoimmune thrombocytopenia.Patients and Methods: Eleven patients with HIV-related thrombocytopenia received dapsone (50 to 125 mg/day) for 2 to 43 months. Patients with the acquired immunodeficiency syndrome were not enrolled.Results: Of the 11 patients, six developed platelet counts above 50 X 10(9)/L and did not require any other specific therapy. No significant side effects were observed.Conclusion: We conclude that dapsone may be effective in some patients with HIV-related thrombocytopenia. [ABSTRACT FROM AUTHOR]