학술논문
Synthesis and evaluation of novel pyrroles and pyrrolopyrimidines as anti-hyperglycemic agents.
Document Type
Journal Article
Source
Subject
Language
ISSN
2314-6133
Abstract
A series of pyrrole and pyrrolopyrimidine derivatives were examined for their in vivo antihyperglycemic activity. Compounds Ia-c,e, and IVg showed promising antihyperglycemic activity equivalent to a well-known standard antihyperglycemic drug, Glimepiride (Amaryl, 4 mg/kg). In this paper, we examine and discuss the structure-activity relationships and antihyperglycemic activity of these compounds. [ABSTRACT FROM AUTHOR]