부산대학교 도서관

Respiratory distress syndrome (RDS) is one of the most frequent respiratory diseases and is a leading cause of neonatal morbidity and mortality. RDS is also known as hyaline membrane disease. Preterm birth is the most important risk factor in the development of respiratory distress syndrome. The maine cause of severe respiratory syndrome is lung surfactant deficiency. Inadequate surfactant production leads to diffuse alveolar atelectasis, edema, cell injury and the decrease of lung compliance. Prenatal diagnosis to identify children at risk, prevention of disease by antenatal administration of glucocorticoids, improving perinatal and neonatal care, advances in respiratory support and surfactant administration , have reduced mortality associated with respiratory distress syndrome. Despite recent advances in perinatal management of severe neonatal respiratory distress syndrome, controversies still exist.(1,3,9) [ABSTRACT FROM AUTHOR]