학술논문

A clustering analysis of eosinophilic asthmatics: Two clusters with sharp differences in atopic status and disease severity.
Document Type
Article
Source
Clinical & Experimental Allergy. Jun2023, Vol. 53 Issue 6, p672-678. 7p. 1 Chart, 1 Graph.
Subject
*ATOPY
*CLUSTER analysis (Statistics)
*ASTHMATICS
*PATIENT compliance
*PATIENT selection
*OLDER patients
Language
ISSN
0954-7894
Abstract
Eosinophilic asthma distributes in two clusters with patients expressing very different disease severity. Here, we have leveraged our large asthma clinic database to perform an unsupervised cluster analysis among asthmatics displaying a sputum eosinophil >=3% ( I N i = 426). While cluster analysis has been largely applied in asthma research over the last 15 years,[6] to the best of our knowledge, there has been no study that specifically focused on eosinophilic asthma as defined by sputum percentage of eosinophils. [Extracted from the article]