학술논문
Conjugated Dienoic Acid Peroxides as Substrates in Chaetopterus Bioluminescence System.
Document Type
Article
Author
Zagitova, Renata I.; Purtov, Konstantin V.; Shcheglov, Aleksandr S.; Mineev, Konstantin S.; Dubinnyi, Maxim A.; Myasnyanko, Ivan N.; Belozerova, Olga A.; Pakhomova, Vera G.; Petushkov, Valentin N.; Rodionova, Natalia S.; Lushpa, Vladislav A.; Guglya, Elena B.; Kovalchuk, Sergey; Kozhemyako, Valeri B.; Mirza, Jeremy D.; Oliveira, Anderson G.; Yampolsky, Ilia V.; Kaskova, Zinaida M.; Tsarkova, Aleksandra S.
Source
Subject
*BIOLUMINESCENCE
*PEROXIDES
*UNSATURATED fatty acids
*FATTY acid derivatives
*
*
*
Language
ISSN
1661-6596
Abstract
Biochemistry of bioluminescence of the marine parchment tubeworm Chaetopterus has been in research focus for over a century; however, the results obtained by various groups contradict each other. Here, we report the isolation and structural elucidation of three compounds from Chaetomorpha linum algae, which demonstrate bioluminescence activity with Chaetopterus luciferase in the presence of Fe2+ ions. These compounds are derivatives of polyunsaturated fatty acid peroxides. We have also obtained their structural analogues and demonstrated their activity in the bioluminescence reaction, thus confirming the broad substrate specificity of the luciferase. [ABSTRACT FROM AUTHOR]