학술논문
Genetic polymorphisms and childhood acute lymphoblastic leukemia: GWAS of the ESCALE study (SFCE).
Document Type
Article
Author
Source
Subject
*LYMPHOBLASTIC leukemia
*GENOMICS
*SINGLE nucleotide polymorphisms
*B cells
*QUALITATIVE research
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Language
ISSN
0887-6924
Abstract
The article presents the results of the genome-wide association studies (GWAS) conducted on the cases of acute lymphoblastic leukaemia (ALL) from the nationwide registry-based study and generic controls of Etude Sur les Cancers et les Leucémies de l'Enfant (ESCALE). The case-control study considered single-nucleotide polymorphisms (SNPs) associated with AL in the GWAS. The positive relationships between common B-cell ALL subtypes and ARID5B SNPs were also observed.