학술논문

Burden of respiratory viral infection in persons with human immunodeficiency virus.
Document Type
Article
Source
Influenza & Other Respiratory Viruses. Jul2020, Vol. 14 Issue 4, p465-469. 5p.
Subject
*HIV infections
*RESPIRATORY infections
*VIRUS diseases
*HIV
*REVERSE transcriptase polymerase chain reaction
*AIDS
Language
ISSN
1750-2640
Abstract
This study was conducted to determine the prevalence of respiratory viral infections (RVI) in persons living with HIV (PLH) admitted with a respiratory complaint using real‐time reverse transcription polymerase chain reaction and primer‐independent next‐generation sequencing (NGS). Of 82 subjects, respiratory viruses were the most common pathogen identified in 27 (33%), followed by fungus and bacteria in 8 (10%) and 4 (5%) subjects, respectively. Among subjects with RVI, 11 (41%) required ICU admission and 16 (59%) required mechanical ventilation. The proportion of respiratory viruses identified, and the associated complicated hospital course highlights the significant role that RVIs play in the lung health of PLH. [ABSTRACT FROM AUTHOR]