부산대학교 도서관

Dietary exposure to organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs), generically named organochlorine compounds (OCCs), now represents a significant health risk for humans due to their endocrine-disrupting and carcinogenic effects. To assess the potential health risk associated with raw milk consumption, 10 milk samples were collected from a local market in the Baia-Mare industrial area, Romania. The concentrations of OCPs and PCB congeners in these samples were determined by capillary gas chromatography with electron-capture detection, after liquid--liquid extraction. In all samples, the OCCs were below the maximum admitted concentrations set by European legislation. The predominant compounds were 4,4'-DDE (11.5 ng/g lipid wt.), β-HCH (10.1 ng/g lipid wt.) and PCB180 (5.08 ng/g lipid wt.). Exposure assessment through milk consumption was performed for male, female and children by calculating the estimated daily intakes (EDIs) and the hazard indices (HIs) for non-carcinogenic effects. The obtained EDIs were lower than the acceptable daily intake values, and HIs were far below 1, indicating no potential health risk for the investigated population. [ABSTRACT FROM AUTHOR]