부산대학교 도서관

Simple Summary: Pulmonary metastases from different primary tumors are a common issue in the everyday clinical praxis. The resection of lung metastases in patients selected by a multidisciplinary tumor board is a widely accepted surgical procedure that can prolong survival. The aim of the current retrospective study is to investigate postoperative morbidity and mortality after pulmonary metastasectomy, identify risk factors and develop a prognostic score to identify high-risk patients. We identified 1284 patients with lung metastases that were resected with curative intent. For increased postoperative morbidity, we identified cardiovascular comorbidities, major lung resections, repeated pulmonary metastasectomy and open thoracotomy. Based on these factors, the Essen score was developed. We believe that the Essen score is a useful tool to predict postoperative morbidity in patients undergoing pulmonary metastasectomy with curative intent. Background: Pulmonary metastasectomy (PM) is a widely accepted surgical procedure. This study aims to investigate postoperative morbidity and mortality after PM and develop a score to predict high-risk patients. Methods: We retrospectively investigated all patients undergoing a PM in our institution from November 2012 to January 2023. Complications were defined as the diagnosis of any new disease after the PM up to 30 days after the operation. Results: 1284 patients were identified. At least one complication occurred in 145 patients (11.29%). Only one patient died during the hospital stay. Preoperative cardiovascular comorbidities (OR: 2.99, 95% CI: 1.412–3.744, p = 0.01), major lung resections (OR: 2.727, 95% CI: 1.678–4.431, p < 0.01), repeated pulmonary metastasectomy (OR: 1.759, 95% CI: 1.040–2.976, p = 0.03) and open thoracotomy (OR: 0.621, 95% CI: 0.415–0.930, p = 0.02) were identified as independent factors for postoperative complications. Based on the above independent factors for postoperative morbidity, the Essen score was developed (overall correct classification: 94.6%, ROC-Analysis: 0.828, 95% CI: 0.795–0.903). Conclusion: PM is a safe surgical procedure with acceptable morbidity and low mortality. The aim of the Essen score is to identify patients that are associated with risk for postoperative complications after PM. [ABSTRACT FROM AUTHOR]