학술논문

Intestinal linoleic acid contributes to the protective effects of Akkermansia muciniphila against Listeria monocytogenes infection in mice.
Document Type
Article
Source
iMeta. Jun2024, Vol. 3 Issue 3, p1-8. 8p.
Subject
*LINOLEIC acid
*ENTEROTYPES
*LISTERIOSIS
*LISTERIA monocytogenes
*MYOSIN light chain kinase
*INTESTINES
Language
ISSN
2770-5986
Abstract
This article explores the role of Akkermansia muciniphila, a type of gut bacteria, in preventing Listeria monocytogenes infection in mice. The study found that mice treated with A. muciniphila had reduced bacterial loads and improved intestinal barrier function compared to control mice. A. muciniphila was also found to increase levels of linoleic acid in the intestines, which strengthened the epithelial barrier and protected against L. monocytogenes infection. These findings suggest that A. muciniphila or linoleic acid-based strategies could be potential approaches for preventing listeriosis. [Extracted from the article]