학술논문
Guidelines for the diagnosis and treatment of neuroangiostrongyliasis: updated recommendations.
Document Type
Article
Author
Source
Subject
*DIAGNOSIS
*RAT diseases
*POLYMERASE chain reaction
*CENTRAL nervous system
*TASK forces
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*
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Language
ISSN
0031-1820
Abstract
A subcommittee of the Hawaii Governor's Joint Task Force on Rat Lungworm Disease developed preliminary guidelines for the diagnosis and treatment of neuroangiostrongyliasis (NAS) in 2018 (Guidelines, 2018). This paper reviews the main points of those guidelines and provides updates in areas where our understanding of the disease has increased. The diagnosis of NAS is described, including confirmation of infection by real-time polymerase chain reaction (RTi-PCR) to detect parasite DNA in the central nervous system (CNS). The treatment literature is reviewed with recommendations for the use of corticosteroids and the anthelminthic drug albendazole. Long-term sequelae of NAS are discussed and recommendations for future research are proposed. [ABSTRACT FROM AUTHOR]