학술논문
Rapid Analysis of Lewisite Metabolites in Urine by High-Performance Liquid Chromatography-Inductively Coupled Plasma-Mass Spectrometry.
Document Type
Article
Author
Source
Subject
*LEWISITE (Poison gas)
*LIQUID chromatography
*METABOLITES
*INDUCTIVELY coupled plasma mass spectrometry
*URINALYSIS
*
*
*
*
Language
ISSN
0146-4760
Abstract
The article discusses the study which examines the effectiveness of the high-throughput method in determining the exposure of Lewisite by measuring the urine metabolite 2-chlorovinylarsonous acid (CVAA) and the oxidized metabolite 2-chlorovinylarsonic acid (CVAOA). It analyzes the urine sample through liquid chromatography-inductively coupled plasma mass spectrometry. It indicates the sensitivity of the selective method that yields no false positive results in 100 urine samples.