학술논문
Gums make IL-23, no professionals needed.
Document Type
Article
Author
Source
Subject
*T helper cells
*EPITHELIAL cells
*PERIODONTITIS
*DYSBIOSIS
*PROFESSIONAL employees
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Language
ISSN
1074-7613
Abstract
IL-23 activates pathogenic Th17 cells to drive inflammatory disease at barrier surfaces. Kim et al. now identify oral epithelial cells as the critical producers of IL-23 in human and mouse periodontitis, linking microbial dysbiosis to non-hematopoietic regulation of IL-17-associated inflammation. [ABSTRACT FROM AUTHOR]