부산대학교 도서관

Indication for IUT Question 1 The indication for IUT in our institution has to date been limited to red cell alloimmunization due to anti-D. Alpha thalassaemia and congenital infections such as Parvovirus are not uncommon in this region of the world, but the foetal and neonatal specialists in our centre have generally not advocated IUT for them. Switzerland Indication for IUT Question 1 IUT is performed based on the following indications: Red cell alloimmunization Foetal anaemia due to parvovirus Feto-maternal haemorrhage Twin-To-Twin Transfusion Syndrome Alpha thalassaemia Platelet transfusion Twin anaemia polycythaemia sequence (TAPS) Question 2 At our institute, alloimmunization during pregnancy leading to an IUT is mostly caused by anti-D. This is in line with the current literature, highlighting the importance of anti-D alloimmunization during pregnancy despite the successful RhD prophylaxis in women 1. Question 2 For the sporadic cases of red cell alloimmunization, we have, in our institution, the common antibodies considered to be clinically significant for IUT are anti-D, anti-c, anti-C and anti-E. Question 3 During the year of 2018, we did not perform any case of IUT. Question 2 The most common antibodies are anti-D, anti-c and anti-K, but we have also performed IUT with combination of anti-C,D,G,E and combination of anti-Fya, Jkb, and D. Question 3 18 supernatant removed RBCs were prepared for IUT by our institution in 2018. [Extracted from the article]