부산대학교 도서관

Simple Summary: Vulvar lymphomas are uncommon diseases and account for less than 0.5% of gynecological cancers and 1.5% of all NHLs. The various types of lymphomas have recently been identified as separate diseases and not as morphological variations of the same disease, according to the World Health Organization classification. They often represent the secondary localization of systemic disease, and diffuse large B-cell lymphoma is the most common type. We also considered cases of vulvar T-cell lymphomas. The data analysis highlighted the difficulty of diagnosis and the need to resort to biopsy–histological examination, as well as molecular methods. The correctness of the diagnosis directly affects appropriate therapeutic management, which requires an adequate surgical approach that can be integrated with chemotherapy and radiotherapy. Since they are very rare tumors, lymphomas of the vulva are often not properly recognized. Patients with vulvar lymphoma are generally elderly and the classical manifestation of the disease is a vulvar mass. No significant age differences have been found between primary and secondary lymphoma. To make a correct diagnosis, it is therefore necessary to use not only histological examination but also the genetic and molecular profile in order to establish optimal therapeutic management. Literature analysis confirm the good prognosis of this disease. [ABSTRACT FROM AUTHOR]