부산대학교 도서관

This article, published in the journal Endoscopy, presents the findings of a multicentre cohort study conducted in 50 Italian hospitals. The study aimed to evaluate the impact of the interaction between bleeding severity and timing-to-endoscopy on the risk of death in patients with upper gastrointestinal bleeding. The study included 2,525 patients, with the majority being male and the bleeding being non-variceal in nature. The results showed that as bleeding severity increased, the risk of death also increased. However, the timing to endoscopy did not significantly affect mortality in patients with low and intermediate bleeding severity. In patients with high bleeding severity, the lowest mortality was observed when endoscopy was performed within 6-12 hours. Overall, the study suggests that bleeding severity is a significant factor in determining the risk of death, while the timing to endoscopy may have a limited impact in certain cases. [Extracted from the article]