학술논문
Silica-bonded N-propylpiperazine sodium n-propionate as an efficient recyclable catalyst for one-pot synthesis of 2-amino-4-aryl-4 H,8 H-6-methyl-8-oxo-pyrano[3,2- b]pyran derivatives.
Document Type
Article
Author
Source
Subject
*AROMATIC aldehydes
*SILICA
*PIPERAZINE
*SODIUM propionate
*PYRAN derivatives
*AMINO compound synthesis
CATALYSTS recycling
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Language
ISSN
0922-6168
Abstract
An efficient and convenient method for synthesis of a series of 2-amino-4-aryl-4 H,8 H-6-methyl-8-oxo-pyrano[3,2- b]pyran derivatives by one-pot, three-component reaction of an aromatic aldehyde, malononitrile or a cyanoacetate, and 5-hydroxy-2-methyl-4 H-pyran-4-one (allomaltol) in the presence of a catalytic amount of silica-bonded N-propylpiperazine sodium n-propionate (SBPPSP), in aqueous ethanol, is described. The method has the advantages of short reaction time, mild reaction conditions, high yields, and convenience. [ABSTRACT FROM AUTHOR]