부산대학교 도서관

Background: Diabetes is a chronic disease involving pancreases. Prevention of the complication among the diabetic patients is through prompt and aggressive treatment aimed at maintaining normal blood sugar levels. One of the most common complication of diabetes is diabetic retinopathy, which is one of the leading cause of blindness. Objective: To prove the hyperactivity of HPA axis in uncontrolled diabetes and hypercortisolism fasten the progression of diabetic retinopathy. Methods: A Cross Sectional study was conducted in a Government Tertiary care hospital in Mysuru city between November 2020 to October 2022. The study population were known case of Type 2 Diabetes Mellitus. Sample size was estimated to be 100. Purposive sampling was used. Results: The study conducted on type 2 diabetic patients. The mean age was 56.8. themale:female ratio in the study was 47:53. The study showed significant correlation between serum cortisol with duration of diabetes, FBS, PPBS, HbA1c. The also showed a positive association between serum cortisol levels with diabetic retinopathy severity. Conclusion: Serum Cortisol levels are High in uncontrolled Diabetes and it implies the risk of faster progression of diabetic retinopathy. [ABSTRACT FROM AUTHOR]