학술논문
mcr-1 Colistin Resistance in ESBL-Producing Klebsiella pneumoniae, France.
Document Type
Journal Article
Author
Source
Subject
*KLEBSIELLA pneumoniae
*COLISTIN
*DRUG resistance in bacteria
*FUNGAL meningitis
*PLASMIDS
*PUBLIC health
*THERAPEUTICS
*ANTIBIOTICS
*COMBINATION drug therapy
*DRUG resistance in microorganisms
*GENES
*GENOMES
*HYDROLASES
*KLEBSIELLA
*MICROBIAL sensitivity tests
*TREATMENT effectiveness
*KLEBSIELLA infections
*SEQUENCE analysis
*PHARMACODYNAMICS
*DIAGNOSIS
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Language
ISSN
1080-6040
Abstract
We report intestinal carriage of an extended-spectrum β-lactamase-producing Klebsiella pneumoniae strain with high-level resistance to colistin (MIC 24 mg/L) in a patient in France who had been hospitalized for fungal meningitis. The strain had the mcr-1 plasmid gene and an inactivated mgrB gene, which are associated with colistin resistance. [ABSTRACT FROM AUTHOR]