학술논문
Relationship between status of plasma atrial natriuretic peptide and heart rate variability in human subjects.
Document Type
Article
Author
Source
Subject
*BLOOD plasma
*NATRIURETIC peptides
*HEART beat
*AUTONOMIC nervous system
*BLOOD sampling
*URINE
*SYMPATHETIC nervous system
*ELECTROCARDIOGRAPHY
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Language
ISSN
0910-8327
Abstract
A relationship may exist between plasma atrial natriuretic peptide (P-ANP) and heart rate variability (HRV), which reflects the activity of the autonomic nervous system. We performed a survey in human subjects to examine the relationship between P-ANP and HRV parameters. Three ethnic groups (Han, Uygur, and Kazakh) provided blood and urine samples and underwent 24-h ambulatory blood pressure monitoring and 24-h ECG recording (24-h Holter ECG). There was a positive correlation between P-ANP and HF, as well as a negative correlation between P-ANP and the LF/HF ratio, in all subjects from the 3 ethnic groups. There was no association of BP with any of the blood, urinary, and HRV parameters. Our results suggested the possibility of a relationship between P-ANP and HRV, which reflects autonomic activity. These findings are consistent with the previous report of a close relationship between ANP and cardiac parasympathetic and/or sympathetic activity. [ABSTRACT FROM AUTHOR]